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In this study, using a neuronal cell line, we show that RIG-I acts with STING in a concerted manner following its interaction with Japanese encephalitis viral RNA to induce a type 1 interferon response.
Using a tamoxifen-inducible Cre line we show that embryonic lethality can be rescued early in gestation but not late.
In this line, we show that neurexin-CTFs appear as two distinct species of ∼12 15 kDa, suggesting the possibility that, similarly to APP, differential cleavage in the extracellular domain of neurexin generates CTFs of distinct sizes.
Using a dmrt2 mutant mouse line, we show that this gene is not involved in symmetric somite formation and does not regulate the laterality pathway that controls left-right asymmetric organ positioning.
In simulations with stabilizing selection in the low line, we show that this can lead to fixation of the L allele for all four loci in the network.
Using this line, we show that Tbr2+ IPCs give rise to both upper and lower layer neurons but in different proportions.
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Using HT29-MTX, a mucus producing cell line, we showed that acetate increases KLF4 abundance.
Using a human astrocytic cell line, we showed that the class I enzyme HDAC3 also promotes expansions.
Using the Tg(CMV EGFP-map1lc3b) line, we showed highly aCMV EGFP-map1lc3bn of GFP-linepositive vesicles upon infection of M. marinum in the tail fin.
Along this line we showed that both airway resistance and specific airway resistance can augment in the presence of peripheral airway obstruction [ 25, 26].
Using a mucus-producing cell line, we showed that acetate up-regulated KLF4, a transcription factor involved in goblet cell differentiation.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com