Sentence examples for line we demonstrate from inspiring English sources

Using DNase-seq measurements assayed in a lymphoblastoid cell line, we demonstrate the improved performance of this model for several transcription factors by comparing against the Chip-seq peaks for those factors.

Using the Ins-1 rat insulinoma line, we demonstrate that activated Rap1A, but not related monomeric G proteins, promotes ribosomal protein S6 phosphorylation.

Using murine whole splenocyte preparations and the human Jurkat T cell line we demonstrate that KLK6 robustly supports cell survival across a range of cell death paradigms.

While only in a single breast cancer cell line, we demonstrate the potential for progesterone to activate EGFR signalling, consistent with progesterone potentiation of EGF responses in ZR-75-1 cells [ 48].

Using phosphokinome profiling and immunofluorescence in the TF-1a cell line, we demonstrate that the drug combination is characterised by the activation of a DNA damage response (induction of γH2A.X and thr68 phosphorylation of chk2).

Using a suitable cell line, we demonstrated the sensitising activity of quercetin.

Using HCT116 parental (KRAS G13D/+) and the isogenic HCT116 (KRAS −/+) cell line, we demonstrated that loss of PTPRS had no or minimal effect on EGFR phosphorylation in mutant KRAS HCT116 cells following EGF stimulation whereas wild-type KRAS HCT116 cells lacking PTPRS had a more prolonged activation of phospho-EGFR compared to the control cells containing PTPRS (Fig. 6c,d).

With the new TRH-Gal4 line, we demonstrated that serotonergic neuron function is involved in the escalation of fights to higher intensity levels.

By using the unique AR cell line, we demonstrated that RSV amended the expression of AR target genes by affecting AR transcriptional activity.

Using the murine macrophage RAW 264.7 cell line, we demonstrated that mmu-miR-665, wasch was dysregulated during colonization, down-regulated Abcc3 expression by directly targeting the Abcc3 3'-UTR.

Using a human T cell line, gene-modified to express a tumor-specific CIR on their surface, and a human tumor cell line we demonstrated that combining CIR-mediated activation with FACS sorting of CD69+ T cells, it is possible to isolate binders to tumor specific cell surface antigen, with an enrichment factor of 103-fold after two rounds.