Sentence examples for line resistant to from inspiring English sources

An MCF-7 cell line resistant to ZA exhibited cross-resistance to several chemotherapeutic agents, and expressed an increased Bcl2/Bax ratio and increased ABC transporters BRCP and LRP [ 64].

A series of 25 phenothiazines and structurally related compounds was investigated by QSAR (quantitative structure activity relationship) and 3D-QSAR methods with respect to their MDR (multidrug resistance) reversing activity in P388/ADR- murine leukemia cell line resistant to ADR (adriamycin).

In fact, in the IRBB4 isogenic line, resistant to both strains, the lesion caused by BAI3 was three times bigger than the one caused by PXO61.

Cancer cell lines sensitive to our compounds express message for the Cav3.2 T-type Ca2+ channel isoform, its δ25B splice variant, or both, while a cell line resistant to our compounds does not.

Especially, the compounds 3a and 3k also exhibited high cytotoxic activities (3a, 19.38 ± 3.38 μM; 3k, 15.43 ± 3.54 μM) against the BEL-7402 celineine resistant to Taxol (>25 μM) and 5-FU (>500 μM), which might be developed as novel lead scaffold for potential anticancer agents.

At least one previous study reported that a CD40 positive tumour cell line resistant to Fas cytotoxicity was susceptible to TNFR or CD40-mediated death [47].

These results may have been expected because cross-resistance between cell lines resistant to these drugs has frequently been documented in the literature [ 31– 31].

In our results, we did not observe any cross-resistance between the W1CR line and other cell lines resistant to cisplatin.

We observed high cross-resistance to doxorubicin, vincristine, and paclitaxel in the cell lines resistant to these agents.

To address this issue in the case of drug resistance, we constructed biological association networks of genes differentially expressed in cell lines resistant to methotrexate (MTX).

Several parasite lines resistant to the anti-babesial drug blasticidin (bsd) and constitutively expressing the gfp-bsd gene were generated after transfection.