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(log virus copies were 5.074±0.2850/ µg total RNA in the BALB/c mice, 5.477±0.08649/ µg total RNA in the write C57BL/6 in one line mice and 3.798±0.04081/ µg total RNA in the ICR mice), whereas the C57BL/6 mice maintained a level similar to the 3 d.p.i.
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We further showed that glutarylation suppresses CPS1 enzymatic activity in cell lines, mice, and a model of glutaric acidemia type I disease, the last of which has elevated glutaric acid and glutaryl-CoA.
The extract showed the inhibition of various cell lines (mouse and human) with special mention of lymphoma and leukemic cells [ 18].
(D ) 16 kHz ABR waveforms of 16 control (blue line) and 16 Mafb CKO (red line) mice were averaged and overlaid.
The WT CD1 strain and TGFα-transgene expressing MT42 line mice grew similarly and showed no noticeable difference in their features, behaviors, or lifespans.
Here, we document the features of cerebellar amyloid in the PrP.HuAβ/PS1 and the PrP.MoAβ/PS1 mice made by co-injecting the transgenes.> -wrap-foot> +: 1 5 plaques, ++: 6 20 plaques, +++: >20 plaques *Age analyzed Cerebellar amyloid occurs in two distinct lines of PrP.HuAβ/PS1 mice; the widely-used Line 85 mice and a sister line mice designated Line 57 [ 20] (Table 1).
As a template, 2.5 µl of cDNA purchased from Clontech (Mountain View, CA) was used (Human I, II, Fetal, Cell Line, Mouse I, and Rat I).
Chromatin immunoprecipitation was performed in a cell line, mouse ileum and human IM.
In total 12 of each Lean and Fat line mice were analyzed.
The difference in time to death between the two HD171-eGFP lines of mice and the HD-N171-82Q line 81 mice can be explained by the level of mutant htt expression.
We next established the Cp-GFP/mdx mouse model through crossing the two lines of mice and examined Cp-GFP expression.
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