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The EOC cell line lines exhibited unique patterns of gene expression as shown by the hierarchical cluster analysis.
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The control cell lines exhibited better healing abilities than the NS1 over-expression cell lines.
Among the cyclohexanone series 1 10, compound 4 was the most potent cytotoxic against four cancer lines especially breast can cell lines exhibited (IC50 = 11.04 ± 2.80, 6.50 ± 01.80, 8.70 ± 3.10 and 2.30 ± 1.60 µg/mL), respectively.
Seven of the medulloblastoma lines exhibited MIBG binding.
Surprisingly, only 19 lines exhibited a survival rate over 70%%.
In the P1 cell lines, 3/8 (37.5%) of the cell lines exhibited a STAT1 expression score ≥0.8, classifying them as STAT1H.
Of note, although comparably robust levels of exogenous wild-type dTip60 were observed for dTip60WT fly lines A and B, unlike dTip60E431Q fly lines, both dTip60WT fly lines exhibited normal phenotypes.
Among the gentian lines, two lines (#5 and #8) exhibited low expression of sGFP mRNA, but all other lines exhibited no sGFP expression in the leaf tissues of in vitro cultured plants (Figure 1C).
Similarly to primary colorectal tumors, these cancer cell lines exhibited high variability in LINE-1 methylation, ranging from 6.5% (K562, a CML cell line with erythroleukemia features) to 74.2% (CEM, an acute lymphoblastic leukemia cell line).
Two lines exhibited a similar phenotype.
Three of these lines exhibited characteristics of erythroid cells.
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