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According to previous cell line experiments and previous experiences, the cutoff level for promoter hypermethylation was set at 15%2931 315%2931
But it's catching up – cuts are slimmer without being skinny, and the younger London line experiments with seasonal shade and shape.
To perform the line experiments, the top three inbred lines from each of the 11 cycles evaluated comprised the 33 evaluated treatments.
Taken together, findings of the experiments with zebrafish embryos recapitulated those of human cultured cell line experiments.
As expected based on data from leukemic cell line experiments, FLT3L activated the MAPK and PI3K pathways inducing increased levels of p-Akt and p-S6 [30] [37].
This concept is supported by cell line experiments demonstrating that BORIS expression by itself is sufficient to simultaneously demethylate and activate the transcription of these genes.
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A promoter methylation ratio > 0.15 (corresponding to > 15% methylation) was regarded as indicative for promoter hypermethylation, based on cell-line experiments and previous experience [ 4, 18].
Fig. 10 Captured color images used in off-line experiments.
Three of the values are also used for evaluation (see "Off-line experiments" section).
In the off-line experiments, three types of methods were applied.
In the off-line experiments, the proposed method is compared with previous methods.
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