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25 26 Sex-specific estimates of RR at varying levels of alcohol consumption were available only for hypertensive disease and liver cirrhosis, and no age-specific estimates were available, which limits the specificity of the counterfactual scenarios analysed by the model.
This limits the specificity of IL-18 in the setting of mixed AKI and pronounced inflammation.
Moreover, we did not include a clinical comparison group, which limits the specificity of the present findings.
However, at the moment, inflammatory status and prematurity limits the specificity of total NGAL measurement as a marker of AKI [ 104].
Caregivers are included within some of the ICPS concepts but failure to include the role of caregivers, and particularly caregiver outcomes, at the class level limits the specificity of the framework in capturing safety issues within the homecare setting.
The sensitivity of HPV testing is good; however, the high prevalence of transient HPV infections limits the specificity of this approach, resulting in high number of colposcopic referrals and unnecessary anxiety for women.
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18F-MK-9470 produces radiometabolites, which limit the specificity of the tracer for imaging CB1R in a peripheral setting [30].
Therefore, the analysis was focused on these groups of patients to identify other risk factors not included in the L-ARRCO score that limit the specificity and sensitivity of the score.
It may also limit the specificity and selectivity of aptamer targeting because of steric hindrance between the target tumor cells and the nanoparticles, such as when aptamer DNA "lies down" on the nanoparticle surface [27].
Despite the sensitivity of dynamic contrast-enhanced imaging for the detection of progressive tumours after ablative therapy, areas of residual benign prostatic hypertrophy may show hypervascularity, thereby yielding false-positive findings and limiting the specificity of dynamic contrast-enhanced imaging [63].
However, other reports noted that cross-reacting antibodies from infection with other subtypes limited the specificity of the assay [35] [37].
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