Sentence examples for limits the function of from inspiring English sources

48, 51 These observations strongly suggest that, in steady-state hematopoiesis, TET2 limits the function of HSCs such as self-renewal and LTR capacities, and functional disruption of TET2 either by gene-targeting or disease-associated mutations would lead to aberrantly elevated HSC capacities and subsequent amplification of multipotent progenitor/CMP fraction.

ABCLibScript limits the function of auto-tuning to numerical computations.

This situation limits the function of public parks as social integrators.

If a painful pseudo-arthrosis limits the function of a shoulder, fractured ends should be fixed until union occurs.

Hence, Pol δ-PCNA does not function with CMG and severely competes and limits the function of Pol α with CMG.

Another effect is the intracellular accumulation of glutamate, derived from the transamination of alpha-ketoglutarate; glutamate limits the function of ATP-dependent cellular pumps, inducing failure to maintain cellular electrolyte homeostasis.

Emphasizing the individuality of the independent organism limits the functions of immunity, which when regarded solely in terms of defense omits the other half of the ledger, i.e., the organism's co-operative intercourse with the environment.

How do we explain that short telomeres limit the function of tissues of slow turnover?

In contrast to the bone marrow failure phenotype which is prominent in the setting of short telomeres, our data indicate that telomere reserves limit the function of tissues of relatively slow turnover such as β-cells.

In general, the influence of different immunosuppressive drugs on NK cell function is of particular interest as it has recently been demonstrated that steroids and calcineurin inhibitors limit the function of IL-2-activated NK cells [28], [29].

Another mechanism limiting the function of transplanted cells for cartilage repair is aging or senescence.