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It would appear, from this initial analysis, that there is substantial transcriptional drive to promote mir-21 expression, while some aspect of the miRNA biogenesis pathway limits substantial production of this translational blocking RNA species.
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The hurricane weakened over Florida while curving to the north and north-northeast, although the proximity to water and the passage over the Everglades limited substantial weakening.
Finally, both investigators and industrials might opt to prematurely stop the assay before the MTD level in order to limit substantial time and resource consuming process.
In our study, the ventilation improved incrementally as the area contributing to ventilation increased, though many homes had only a few small windows, limiting substantial increases.
The effects of microtube diameters on the stability limits were substantial only for the methane air microflames of lower mixture temperature.
The implication is that if the price of preventive medication increases above certain limits, a substantial proportion of the population may potentially refrain from treatment.
Thus, if the price of preventive medication increases above certain limits, a substantial proportion of the population may refrain from treatment.
The elastic modulus of the network is found to correlate strongly with the number of elastic strands in the network, except at the highly-crosslinked limit where substantial discrepancy is observed between networks from different precursors.
The meta-analysis was limited by substantial inter-study heterogeneity.
The interpretability of health outcome and efficiency differences was limited by substantial variations between the populations.
In florid relapse, however, the efficacy of DLI is limited with substantial risk of severe graft-versus-host disease (GvHD).
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