Exact(10)
MiR27a is overexpressed in human gastric adenocarcinoma, and inhibition of this miRNA limits proliferation [82].
In conclusion, glutamine shortage in K-ras transformed cells limits proliferation by inducing abortive S-phase entrance, while glucose shortage in the same system enhanced cell death [14], [15].
Here, we report the first mechanism that limits proliferation in the pLLP.
This is supported by studies showing that knockdown of KDM4C limits proliferation in mammalian cancer cell lines [ 83– 83].
This leads us to propose that Amotl2a, possibly by forming a ternary complex with Yap1 and β-catenin, limits proliferation in the trailing part of the pLLP.
PROBLEM: Cellular senescence was originally believed to be a cell culture artefact that limits proliferation of normal cultured cells after a finite number of divisions.
Similar(50)
"Altogether, these results suggested that the physical interaction between Amotl2a and Yap1 is required for the proliferation-limiting activity of Amotl2a" (in the subsection "Amotl2a inhibits Yap1 activity to limit proliferation in the pLLP").
Ukraine's act of good will was heralded as a major success of efforts to limit proliferation of nuclear weapons in the world.
The occurrence of mutations in terminally differentiated T cells may discriminate a benign disorder from a malignant transformation (such as leukaemia or lymphoma), because terminally differentiated effector-memory cells have limited proliferation potential.
The purpose of the program was to limit proliferation of nuclear weapons by offering technology for civilian use in exchange for a promise not to pursue military applications.
But talking about creating another nuclear power — the world's 10th — is virtually taboo in Washington, where President Obama has made limiting proliferation and securing nuclear fuel a signature element of his national security policy.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com