The remainder is disposable within the limits of practicality.
This would mean that when being asked to give consent for a NGS-based test, patients should (within the limits of practicality) be given the opportunity to indicate both: which unsolicited findings they would want to be informed about and which not.
Do some adventure brainstorming, and put no limits of practicality or feasibility on your ideas at this point.
Of course, experimental and quasi-experimental evaluation have important limits, in terms of practicality, ethical limits, and the ability to isolate single causal mechanisms in the context of 'open' systems [ 75].
At the same time, as I know from my own experiences of working with her on building projects, her designs do indeed tend to be expensive and hard to achieve, and push to the limits of buildability and practicality, and sometimes beyond.
Further, in [16] environmental features have to be logged for at least 50 user actions, and additional updating requires a history of 50 to 256 votes, which limits the practicality of the method.
The heterogeneous nature of most tumor antigens and patient MHC haplotypes limits the practicality of externally-loaded pre-determined peptides as an antigen source for vaccines.
The vegetation detritus protects seedlings when they are most vulnerable to the ravages of nature, but it also lowers the soil surface temperature and limits the practicality of using the till-less system in some areas to warmer regions or to plant varieties suited to cooler seedling-growing conditions.
Because any electrical current generates a magnetic field, this roadblock greatly limits the practicality of harnessing the electron superhighway effect.
Finally, an ethical dilemma that limits the practicality of designing an RCT is the difficulty in recruiting individuals in the study.
Unfortunately, one of the byproducts of producing Cu with a natural Zn target was Zn (T1/2 = 245 d), which limits the practicality of production by this method [ 27].
