This feature is meant to keep the program away from censors but is also the largest drawback because it limits efforts to get the program to as many people as possible.
Significant genetic heterogeneity across dual genomes and high morbidity associated with mitochondrial RC dysfunction limits efforts to discern the pathogenic mechanisms underlying widespread phenotypic variability in human mitochondrial diseases [25], [26].
Late diagnosis is an important cause of HIV-related morbidity, mortality and healthcare costs in the UK and undiagnosed infection limits efforts to reduce transmission.
Unfortunately, a great deal of stigmatization and discrimination is still associated with HIV+ status, which negatively impacts compliance with ART protocols and thus limits efforts to contain the epidemic.
Limited effort has been devoted to the simulation of non-stationary wind velocity.
However, in contrast to folate, there has been limited effort applied to specifically design and develop Fe chelators for the treatment of cancer.
In situations where the processing load exceeds the capacity limit, effort should reach an asymptotic level or, with overload, reveal a tendency to reduce [32].
Other approaches to mitigating bycatch in marine capture fisheries include input and output controls (measures to limit effort and catch), compensatory mitigation, marine spatial planning, fleet communication, and market-based mechanisms [7], [23].
However, there has been limited effort to synthesize data from these different sources.
