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This result could be explained if in vivo siRNA levels are not limiting so that an increase in siRNAs has no clear impact in target methylation levels.
Release of ADP is rate limiting, so that a screening assay which tests compounds that reduce the steady state ATPase might be useful for looking for such drugs that bind to E·ADP.
This flux could be affected if early steps in glucose metabolism were rate limiting, so that the increased transport of glucose into the muscle cell by low fatty acid availability caused increased export from muscle as lactate, and an 18% increase in plasma lactate has been observed to accompany acipimox-induced suppression of lipolysis during a clamp [ 25].
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Humanitarian aid has also been strictly limited, so that Myanmar receives $2.80 of annual aid per head compared with $55 for Sudan.
Government is limited, so that burdensome regulations never kill jobs.
Capital mobility was limited, so that countries had control over their own monetary conditions.
The board's powers are limited so that ordinary shareholders have little sway over the running of the company.
Group size is limited so that the teenagers get to know one another better, but e-mail addresses are hidden.
In flexible automation, the variety of products is sufficiently limited so that the changeover of the equipment can be done very quickly and automatically.
Most important, the indiscriminate use of antibiotics in both medicine and agriculture needs to be limited so that resistant strains take longer to emerge.
In many other democracies, voters can only vote at one location and are unable to vote remotely – postal voting is either unavailable or limited so that votes can be returned by election day.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com