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Targeting MIF under these circumstances might alter the tumors' capability of withstanding radiation or chemotherapy, thereby increasing effectiveness and limiting side effects.
4030W92, at 25 mg/day, produced a nonsignificant reduction in pain without treatment limiting side effects.
Unlike with testosterone and other anabolic steroids, the action of SARMs and myostatin inhibitors is restricted to muscle, likely limiting side effects.
This provides an excellent framework to aid in the design of novel antipsychotics with diminished propensity to produce clinically limiting side effects.
These proteins are targets for some of the most commonly prescribed medications in dermatology, including corticosteroids, retinoids, and vitamin D analogues, all of which have limiting side effects.
Since the beginning of the use of high-dose pulses of corticosteroid, there was anticipation that there would be significant and limiting side effects.
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However, IFO is subject to limiting side-effects in high-dose protocols.
Brain delivery of GDNF can, however, be associated with limiting side-effects in both primates and PD patients, rendering the duration of delivery a critical factor.
In addition, stimulation of the region is often necessary intraoperatively not only for evaluation of efficacy, but also for evaluation of limiting side-effects.
Dose-limiting side effects were rare.
Dose-limiting side effects of centrally acting opioid drugs have led to the use of topical opioids to reduce the pain associated with chronic cutaneous wounds.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com