Sentence examples for limiting event from inspiring English sources

Based on the ΔCPR criterion, the Lungmen Preliminary Safety Analysis Report (PSAR) concluded that Load Rejection (LR) event was the most limiting event.

Metastatic disease is the most serious and limiting event in sarcomas [ 21, 23, 26, 29, 30, 32].

The data reported above indicate that BMP/Id can maintain Cdh1, and that downregulation of Cdh1 is a limiting event during differentiation of ES cells.

Development of metastasis is the most limiting event in sarcomas [ 21, 23, 26, 30, 31] and is dependent on tumour size and grade [ 13].

Since the mean volume of M1 and M2 cells was similar, it seems that in our model the cell size was not a limiting event in transmigration.

In summary, we have identified the loss of Cdh1 activity as a limiting event for the earliest stages of neural differentiation and we propose that BMP controls differentiation in part by maintaining Cdh1 expression.

Cilengitide might be a particularly well-suited drug to combine with chemotherapeutic agents with the purpose to improve chemotherapy delivery to tumors, which is one of the limiting events in cancer therapies.

Identifying the limiting events in aerobic glycolysis and the response of cancer cells to metabolic inhibition is now essential to exploit this potential metabolic dependency.

The type of events chosen as end points may also have a bearing on the trial size; limiting events to MACE may require more patient-years to accrue compared with a broader spectrum of qualifying events.

If patients experienced significant toxicity other than the defined dose limiting events, treatment was delayed until recovery to grade 0 1, and then restarted, for the subsequent cycles, at the dose level below.

It is also believed that the detachment of cytochrome c from the inner membrane and its release into the cytosol is one of the rate limiting events in the execution of the apoptotic program [ 28].