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While inhaled iloprost provides an alternative to parenteral prostacyclin therapy, the relatively short half-life of the compound requires a frequent dosing schedule potentially limiting compliance and perhaps efficacy.
Exclusion criteria were: (1) previous treatment with TENS or other electrotherapy for diabetic neuropathy; (2) presence of an implanted pacemaker, defibrillator or neurostimulator; (3) presence of an active foot ulcer and/or previous major amputation of the lower extremities; and (4) any concomitant severe disease limiting compliance to study procedures or life expectancy.
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Thermorheological response of each polymer was characterized by tensile creep tests through the glass transition of the soft segments, to obtain the linear viscoelastic retardation spectrum, limiting compliances and time temperature shift factor.
Incomplete lengthening of the capitate was seen in one patient who demonstrated limited compliance.
To prevent small errors in the robot sensory system from affecting the system performance, limited compliance is assumed in robot arms.
California is one of five states that limit compliance with ICE detainer requests and similar policies are in place at 37 cities nationwide, according to the Immigrant Legal Resource Center.
In all three of these trials, significant fatigue, anorexia, and other constitutional symptoms limited compliance and patient willingness to continue therapy.
Other exclusion criteria comprised patients with uncontrolled concomitant illness including but not limited to ongoing or active infection, HIV+ on anti-retroviral therapy, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness that would limit compliance with study requirements.
Research suggests that a low level of education and interest in health issues may limit compliance with recommendations provided through the health system [ 9- 11].
Although the low compliance scores may be in line with other publications reporting limited compliance [ 22, 24], several reasons may be suggested to explain the low estimated compliance in our study.
55 There are many factors contributing to poor compliance: side-effects associated with topical glaucoma treatments can limit compliance and reduce QoL; elderly patients often find eye drops difficult to administer.
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