Sentence examples for limited suppression from inspiring English sources

Even then, viral infection and shRNA expression was limited to a small area around the injection site, resulting in spatially limited suppression of PrPC expression, modestly impeded disease progression and unaltered disease incidence.

Fire management also calls for conscious decisions to allow some wildfires to burn freely or to be subjected to limited suppression action if and when the net benefit of doing so is thought to be positive.

While BRD4 inhibitors have shown some promise in MYC-driven malignancies such as Burkitt's lymphoma (BL), we show that BRD4 inhibitors lead to robust BRD4 protein accumulation, which may account for their limited suppression of MYC expression, modest antiproliferative activity, and lack of apoptotic induction.

While verapamil, nifedipine and diltiazem enhanced radiosensitivity at low doses and increased radioresistance at higher doses, flunarizine, which exhibits only limited suppression of cardiac contractility (Robertson and Robertson, 1996), increased radiosensitivity at all dose levels.

Thus it was observed in this work that suppression was reproducible, but a further assessment of whether limited suppression was reproducible and to what level of precision would need to be undertaken.

In summary, the observed induction of autophagy by both EtOH and INK128 combined with the dose dependent induction of apoptosis by INK128 but not by EtOH treatment further corroborates a limited suppression of mTOR by EtOH, as opposed to the potent mTOR inactivation by INK128 with respect to cellular phenotype and subsequent cell fate.

These studies underscore the consensus opinion that TGFβ1 levels in cancer mediate a neoplastic plexus, driving cancer cells towards more aggressive behaviors and supporting their survival, while simultaneously limiting suppression by the host and perhaps augmenting normal tissue complications.

Although knowledge of the detailed mechanisms is limited, growth suppression of lung adenocarcinoma by the NMDA antagonist MK-801 via inhibition of the ERK pathway and induction of the tumor suppressor protein p21 and p53 has been reported [ 28].

Nilotinib was also able to suppress doxorubicin-induced activation of MAPKs and expression of inflammatory mediators in vivo, although the effects that we detected were limited to suppression of IL-1β RNA in the liver and IL-6 protein levels in the serum (Fig. 4).

Thus, decreased miR-132 levels may negatively impact brain health, through the dysregulation of p250GAP (limiting its suppression) and ACHE (indirectly decreasing acetylcholine levels).

The unclassified portion of material about Libya that the White House sent to Congress last week, for example, said "American strikes are limited to the suppression of enemy air defense and occasional strikes by unmanned Predator" drones, but included no numbers for such strikes.