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CD4+ T-cell testing of blood specimens collected in standard EDTA Vacutainer tubes and transported at ambient temperature, must be completed within 48 hours with the BD FACSCount™ flow cytometer, restricting specimen collection in remote clinics with no on-site testing and limited specimen transport services.
The limited specimen tilting range that is typically available in electron tomography gives rise to a region in the Fourier space of the reconstructed object where experimental data are unavailable – the missing wedge.
Because of limited specimen volume, the complete coding region genome sequence was only obtainable by combining sequence data from DNA fragments generated from 4 patients.
Many authors have pointed out the limited specimen yield of FNAB using smaller gauge needles (25- and 27-G) as a limitation for the widespread use of FNAB.
In a few instances, it was not possible to characterize the virus beyond influenza type A because of limited specimen availability; these cases were assumed to be pandemic (H1N1) 2009.
Particularly in the field of NSCLC, where patient samples are difficult to obtain and testing (molecular and immunohistochemical) is being prioritized for treatment decisions, the efficient use of limited specimen is of great importance.
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In the present health-care environment, it is critical to develop a cost-effective, efficient testing strategy that maximizes the diagnostic potential of even limited specimens.
For instance, Burval et al. [ 16] compared the two augmentation techniques in the same specimen whereas Becker et al. [ 15] limited each specimen to one of the techniques being tested.
While previous anatomical studies have been limited by specimen numbers and study design, computed tomographic angiography (CTA) can demonstrate in-vivo vascular anatomy in large numbers.
As a retrospective review, we were limited by specimen availability, which may have introduced unexpected bias into the results.
The narrower size distribution of oligomers in our analysis (3.85 ± 0.67 nm, Figure 5G) is due to the SEC fractionation which limited the specimen analyzed to a subpopulation of high molecular mass oligomers, compared to unfractionated AβO samples used in previous studies.
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