Sentence examples for limited specificity and from inspiring English sources

However, there are several notable limitations to these techniques, including limited specificity and accountability for compensatory mechanisms.

Piepenbrink, K. H., Blevins, S. J., Scott, D. R. & Baker, B. M. The basis for limited specificity and MHC restriction in a T cell receptor interface.

Even though several biomarkers are in use in diagnosis and prognosis of the disease, they are marred by limited specificity and sensitivity.

However, their limited specificity and their cellular toxicity prompted us to develop a screening assay to target molecules able to inhibit NC chaperone properties, and more specifically the initial NC-promoted destabilization of the nucleic acid secondary structure.

These methods suffer from limited specificity and reproducibility of the counting of WBC and lack of sensitivity in finding of parasites in CSF [11, 12] (Dieudonné Mumba Ngoyi, personal communication).

The limited specificity and sensitivity of current early diagnostic biomarkers has greatly restricted their reliability.

To quote him "if our goal is achieved it would be like reviving all the 'failed due to limited specificity' drug substances and giving them a new orientation and a second chance to offer a cure that nobody could have imagined before".

It may be argued that, due to the limited specificity of FFA and 2-APB, the effects of both compounds described above may be due to an inhibition of volume-sensitive outwardly rectifying (VSOR) Cl− channels (see [ 2, 18] for review), rather than blockage of the HICC.

While 1h due to its limited specificity towards ATGL and intrinsic toxicity will be less useful as molecular probe than Atglistatin (B), the SAR studies presented in this manuscript have provided more insight into the characteristics of the ligand binding pocket of ATGL for the first time.

The algorithms showed limited sensitivity for COPD, depression and osteoarthritis, poor PPV for COPD and limited specificity for hypertension.

The blood brain barrier (BBB), systemic cytotoxicity, and limited specificity are the main obstacles in designing brain tumor drugs.