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Exact(21)
However, limited sequence identity, distinct architecture, and the absence of experimental data have made this assignment ambiguous.
IF proteins exhibit rather limited sequence identity implying that the different types of IFs have distinct biochemical properties.
PS2Aa1 shows a remarkable structural similarity to the aerolysin-type β-PFTs, which is much greater than expected from its limited sequence identity to those toxins.
The two sequences could be well aligned despite limited sequence identity (36%).
This limited sequence identity suggests the involvement of nonhomologous end joining (NHEJ), a pathway responsible for repairing double-strand breaks in DNA [16].
Both of these proteins adopt an overall fold similar to the papain sub-family of cysteine proteases, as originally identified in the structure of a truncated form of Cif from Enteropathogenic E. coli (EPEC), despite sharing only limited sequence identity.
Similar(39)
A recent study on the GPCR repertoire in the Branchiostoma floridae genome reports two cAMP GPCR-like sequences with limited sequence identities [ 12].
PfAlba6 is highly diverged from rest of the group with only limited sequence identities with other Plasmodium Alba proteins (Fig. 4b and c).
Although the putative non-GRAFS Ciona GPCRs ci0100132129 and ci0100150391 cluster with cAMP and Methuselah GPCR families with significant bootstrap support, they share only limited sequence identities (~19 25 %) with homologous members of their respective families.
RF2 of LD-CMS showed limited amino acid sequence identity (28%) to GRP162 but lacks an RNA recognition motif.
Interestingly, the three human Saps identified, named PP6R1, PP6R2, and PP6R3, were shown to physically interact with human PP6 and share limited amino acid sequence identity (10%) with the four yeast Saps [17].
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