Sentence examples for limited responsiveness from inspiring English sources

Previous studies of primary HIV-1 infection have shown limited responsiveness to several HLA-A2-restricted CTL epitopes [54], [55], [56], [57], even though responses against the HIV Gag 77-85 (SL9, 77SLYNTVATL85) epitope becomes immunodominant in chronic infection [55], [56], [58].

Pain, overall health, falls/psychological factors, and total score of the JOQOL seem to have limited responsiveness to treatment changes.

In tolerant varieties, ethylene-promoted induction of SUB1A results in limited responsiveness to bioactive gibberellin (GA) because of increases in the GA response repressors SLR1 and SLRL1.

Effective management of FOG is difficult given its episodic nature, heterogeneous manifestation and limited responsiveness to drug treatment.

Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related deaths in the world, showing only limited responsiveness to conventional anticancer agents.

Due to the limited responsiveness of generators, fast and accurate demand side resources (DSR) have recently been encouraged to participate in FR.

Tofacitinib inhibits JAK3- and to a lesser extent JAK-2-mediated phosphorylation of activated cytokine receptors and subsequently limits responsiveness to pro-inflammatory cytokines (Pesu et al., 2008).

We note that the half lives of EGFP and EYFP are in the order of 24 h [55], limiting their responsiveness to fluctuations with timescales of less than one cell generation (∼15 h).

Sepsis-induced cardiac dysfunction may limit fluid responsiveness and the mechanism thereof remains unclear.

Indeed, right ventricular dysfunction caused by moderate pulmonary hypertension (which was not monitored in this study) has been described to limit fluid responsiveness before [ 6, 39].

Furthermore, the profile of other negative regulatory proteins is complex, and in theory could compensate for, or synergize with existing SOCS proteins to limit cytokine responsiveness in the cell.