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In many cases, the use of bypass surgery or balloon angioplasty is limited, necessitating amputation.
Current therapies to retinoblastoma are limited necessitating the patient to undergo enucleation.
Natural sources of fixed nitrogen, the form easily available as fertilizer for plants, are limited, necessitating artificial fertilizer production.
However, the results in these researches are contradictory, moreover, the identified targets by which miR-7 exerts its function are still limited, necessitating studies for further elucidation.
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The characteristics of these types of problems extend considerably beyond the linear elastic limit, necessitating the use of both kinematic and material nonlinearities.
While the main burden in the 16th century fell on the ecclesiastical courts, their powers over administrators and executors was limited, regularly necessitating the Court of Chancery's involvement.
The non-linear, unexpected and severe responses of ecosystems to the environmental changes crossing ecological thresholds or environmental limits, necessitate the regular monitoring of the human-induced pressures to the urban ecosystems.
Existing mechanical and bioprosthetic replacement valves are far from ideal, requiring concomitant anticoagulation therapy or having limited durability, thus necessitating further surgical intervention.
However, these curcuminoids suffer from low aqueous solubility, poor bioavailability, and low stability and therefore, have limited practical use, necessitating the modification of their properties in order to develop a versatile, useful and effective therapeutic product [2].
The healing capacity of articular cartilage is limited [ 1] necessitating the development of methods for repairing or replacing damaged tissue.
Similarity of motif compositions between functionally similar CRMs, while presumed above as evidence of shared descent, may also result from parallel evolution, if for instance the "solution space" of a specific regulatory functionality is limited and necessitates a unique combination of binding sites (Crocker and Erives 2008).
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CEO of Professional Science Editing for Scientists @ prosciediting.com