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Ongoing clinical trials may enlarge the actually limited eligible number of CF patients for new drugs such as ivacaftor.
Methods: In order to establish trends and to exclude stable post surgical patients we limited eligible patients to those who were on the unit for 3 days or more.
Because the iHS has its maximal power when selected alleles segregate at intermediate frequency, we limited eligible SNPs to those with MAF > 0.2 in each breed.
Therefore, for our base case, we limited eligible subjects to those born and diagnosed in the same state (SEER provides county of residence at diagnosis but only state of residence at birth).
We limited eligible births for our study to singleton births with known birth order, known maternal race, known maternal education, known marital status, known maternal age, known birth weight, and a reported gestational age of up to 44 weeks.
As a result of limited eligible trials, five retrospective trials were also included in this meta-analysis.
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There are several reasons for this, including the need to identify a responsive population to be able to demonstrate improvement successfully (for example, efficacy and inclusion/exclusion criteria that limit eligible subjects to those without medical conditions that could confound assessment of the safety of the agent).
These criteria limited our eligible sample to 142,346 children with 1,075,237 visits.
Moreover, this approach is associated with a substantial treatment-related morbidity and mortality and is limited to eligible patients.
Of the 2001 2004 NHANES sample, we limited our eligible study population to the 3,272 individuals aged ≥25 years who did not have diagnosed diabetes and had an FPG <126 mg/dl (OGTT was not performed).
When it came to the stimulus package earlier this year, as part of a politically popular move limiting programs eligible for funding, "swimming pools" were explicitly excluded from ARRA funding mechanisms.
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CEO of Professional Science Editing for Scientists @ prosciediting.com