Sentence examples for limited efficacy for from inspiring English sources

Thus far, efforts to inhibit mTOR-associated pathways (e.g., rapamycin) have achieved only limited efficacy for treatment of plaque psoriasis [ 86, 87], although some efficacious topical agents are known to inhibit AKT/mTOR signaling [ 88, 89].

We assess the performance of our classifier and show it to be sufficient for use in forensic triage and 'early warning' of CEM, but of limited efficacy for categorising against existing scales for measuring child abuse severity.

A comprehensive review of the risk benefit of these medicines in COPD is provided here which concludes that there is limited efficacy for LABAs in COPD either alone or in combination with ICS and no overall modification of the disease process.

The opponents will insist that flibanserin is a proverbial "tough pill to swallow," citing limited efficacy for a limited population.

As all interval cancer cases were associated with smoking, low-dose CT screening showed limited efficacy for nonadenocarcinoma in smokers.

Azacitidine and decitabine are often reserved for treatment of patients with high-risk disease due to their potential toxicities and limited efficacy for lower risk patients.

Current therapies, including surgery, radiation therapy, and chemotherapy, present limited efficacies for treating malignant glioma [1, 2].

The limited efficacy of Trastuzumab for cancer therapy, problems of acquired resistance and the potential impact of novel anti-HER2 antibodies as therapeutic partners or alternative therapeutics justify more investment on HER2 targeting with novel monoclonal antibodies.

The complete lack or limited efficacy of vaccines for rapidly mutating viruses causing chronic infections (e.g., HIV and HCV) or seasonal pandemics (Influenza) is due to the extreme and rapid adaptation dynamics of these viruses at both the within and between host level.

Despite this low-quality evidence, recent VAP management guidelines recommend adjunctive nebulized antibiotic therapy for bacteria that are only susceptible to antibiotics when there is evidence for limited efficacy of the intravenous route, i.e., aminoglycosides and colistin.

Our results may explain the limited efficacy of cytokine therapies for EOC to date.