Sentence examples for limited division from inspiring English sources
The wing disc epithelium is established during embryogenesis, undergoes many rounds of cell division during larval development and is present until eclosion, while follicular cells have a much more limited division potential and a shorter lifetime corresponding to the development of an individual egg chamber during oogenesis.
Unlike stem cells, somatic cells have a limited division capacity and senesce in vitro.
For example, most somatic cells exhibit a limited division potential, whereas the stem cells that generate them can divide indefinitely.
Normal human fibroblasts have a limited division potential and undergo telomere-driven replicative senescence (Herbig et al. 2004; Allsopp and Harley 1995).
Hayflick's hypothesis, that each cell has its own limited division capacity [ 2], received fundamental support with the discovery of telomeric shortening during DNA replication in somatic cells [ 3].
16 Due to the limited division of cardiomyocytes, maintenance of the structural integrity of the heart is accomplished by accumulation of fibroblasts.
Expansion varied from stable, steady cell divisions for most colonies to some with limited divisions followed by degeneration due, we assume, to stem cells present in stable colonies versus committed progenitors in those that degenerated.
We predict that asynchronous, cytoplasmic-resource-limited division is the ancestral condition.
Whereas telomerase activity is generally upregulated in tumors sustaining proliferation and potentiating mutagenesis and transformation of cancer cells [ 54], in IPF limited cell division due to decreased telomerase activity is thought to contribute to the phenomenon of high percentages of apoptotic cells in fibroblasts [ 55].
These results define a physiological role for the WRN RecQ helicase protein in RAD51-dependent HR and identify a mechanistic link between defective recombination resolution and limited cell division potential, DNA damage hypersensitivity, and genetic instability in human somatic cells (Saintigny et al 2002).
The majority of OPCs are quiescent with limited self-division under normal circumstances, but they may respond rapidly to injuries and, in particular, demyelination.
