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We recently reported that mice that are completely deficient in TANK2 expression [18], or mice that express only a mutated form of TANK2 lacking PARP activity [6], manifest similar phenotypes with limited differences from wild type controls.
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For example, the ether-based CAM 1b (PG O–(C16 0.61, 61% of OH groups are O-alkylated by cetyls) is with limited difference from the ester-based CAM 2a (PG COO–(C16 0.60), but they show very different guest selection.
By extending the power transformation into linear mixed model setting with NDNQI examples, we found limited difference from subsequent test of structural effects regardless of whether such structure is included or omitted during the parameter estimation for transformation.
This figure is several-fold higher than those reported from a variety of Leishmania species (i.e., L. major [ 13- 15, 18], L. donovani [ 20], L. infantum [ 17] and L. mexicana [ 16]), which clearly show limited differences using microarrays (ranging from 0.2 to 5% of total genes) in stage-specific gene expression between the promastigote and amastigote life stages.
For example, VBM detects only linear, spatially limited differences [39].
This analysis shows limited differences between the two sets.
The suggested associations, if causal, represent limited differences in prevalence.
There were limited differences between men and women.
Another important finding from our microarray analysis was that there was limited difference in whole genome expression between non-syndromic and syndromic patient samples.
There is, at best, limited difference.
The consequences of this time-limited difference are also unclear.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com