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The main limitation of this study is the small sample size, which may have limited detecting associations of only modest size between COMT gene and deficit/nondeficit subtypes.
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The value of 99% simply reflects the fact that if 1% of the samples are above the detection limit, detecting viruses in a standard monthly, single grab sample will be rare.
In addition, GCTA is limited to detecting the additive effects of SNPs; it cannot detect gene gene (or gene-environment) interaction.
Unenhanced CT is particularly limited to detecting intracranial haemorrhage and brain oedema.
The system looks quite bulky, however, and is limited to detecting objects within a narrow plane, so it wouldn't pick up, say, a curb or overhang.
However, their model is simpler because it is limited to detecting large objects near the camera and moving in the same direction and sense.
The applicability of available methods is limited to detecting and tracking particle size and position only under cold flow conditions being the main weakness of these methods.
Furthermore, RNA-seq is not limited to detecting transcripts corresponding to existing genomic sequences, thus it is especially suitable for non-model organisms [19], [20].
As a carrier test it is limited to detecting full mutation carriers.
Nevertheless, CT is limited in detecting small hepatic or lymph node metastasis.
Both methods are limited to detecting reassortments between collected and sequenced strains.
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