Sentence examples for limited depth of coverage from inspiring English sources
They found more abundant CRISPRs in ice samples relative to soil, possibly indicating higher viral diversity and infectivity rates (although they note this may also be due to limited depth of coverage in the soil metagenome dataset), and evidence for phage-mediated transduction in the bacterial community.
There are only small numbers of such analyses, whilst the diversity of policy areas, topics and analytical issues that have been addressed across a large number of country settings results in a limited depth of coverage within this body of work.
Third is the limited depth of focus.
For a given genomic sequence, this method assesses depth-of-coverage and compares it with the average coverage depth.
Conversely, proteomic analysis is currently much more limited in breadth and depth of coverage owing to variations in protein abundance, hydrophobicity, stability, size and charge.
Unfortunately, that experience is often limited in scope and depth of coverage.
This observation suggests that while a complete coverage saturation of all possible sites may require an excessive number of reads, it is possible to achieve near saturation of sites within a limited size-spectrum at much lower depth of coverage.
53, 60, 80 Compared with exome sequencing and genome sequencing, targeted gene panels with a limited gene number allow: a high depth of coverage, with increasing sensitivity and specificity; a high capacity to interpret the findings in a clinical context; running of more patient samples per cycle (barcoding and pooling); less amount of data generated; and less storage requirements.
The reason for this low detection rate is the limited depth coverage (about 5X) combined with a low non-reference allele frequency among the undetected SNPs.
Limited risk pooling means that insurance and depth of coverage is a common problem for families.
It suggests that in many cases it is not the depth of coverage that is limiting the breadth of coverage.
