Also suppose that due to the limited availability of the intervention, they can enroll at most n = 2000 study participants in each arm.
Notwithstanding the limited availability of evidence-based loneliness interventions, public health policy calls for intervention programmes for the prevention of loneliness and the stimulation of social engagement on the community level [ 17- 19, 31].
The primary limitation was the limited availability of additional patient information (medical record, medical history, outcome of intervention etc).
Different factors can be assumed to explain low rates of treatments, including patients' opinions and preferences [ 10], under recognition of mental disorders [ 11], and, with regards to psychological interventions, limited availability of trained physicians [ 12, 13], poor confidence by PCPs [ 9, 14], and time constraints due to the setting [ 15, 16].
The latter was due to the limited availability of physiotherapy during weekends, which potentially could obscure the effect of the intervention.
The majority of maternal deaths in India can be averted by interventions that address the issue of a limited availability of skilled birth attendance and emergency obstetric care (EmOC) (3– 5).
Several explanations can be invoked for this phenomenon, i.e. low priority of headache in the list of interventions of national health system, insufficient awareness, inadequate preparation of GPs, limited availability of dedicated healthcare structures, stigma and many others [3 8].
Strategic withdrawal, due to the cumulative disappointment of numerous military and civilian stabilisation interventions in fragile or failed states, and more limited availability of resources for such missions [9, 19].
The lack of intervention and treatment strategies for BO can be attributed in part to the limited availability of animal models in which to study disease development.
However, these interventions tend to be led by highly trained health professionals; considerably limiting their long-term sustainability, due to high cost and limited availability of qualified professionals, especially in non-metropolitan areas.
