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We can see that when there is limited availability of compounds, as was the case for older models, an external validation set is not possible.
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Currently, the limited availability of compound DDD00015314 and its expense preclude such analysis with a monomorphic RNAi library (44); however, the enhanced sensitivity of pleomorphic cells could permit this analysis if RNAi libraries could be generated at sufficient coverage in these cell lines.
Another para-hydroxylated metabolite, 4-HO-BDE-42, appears to have been more potent than DE-71, but because of limited availability of this compound, the analysis was not carried out with a sufficient span of concentrations to allow an accurate estimate of the EC50.
Reduction of nitro compounds, RNO2, by hydrogen or other reducing agents produces primary amines cleanly (i.e., without a mixture of products), but the method is mostly used for aromatic amines because of the limited availability of aliphatic nitro compounds.
Due to the limited availability of the lactone compound for testing, 5-hydroxy-2-decenoic acid lactone (abbreviated as HDCL, CAS no: 54814-64-1) was obtained from Penta International Corp., Livingston, USA.
Key to success Achieving universal salt iodization throughout Ghana remains a challenge due to weak law enforcement; limited availability of potassium iodate, the compound used to iodize salt; and the large number of small-scale salt producers, estimated between 5000 10,000, who are difficult to monitor.
In rural areas, effective and timely diagnosis and subsequent appropriate treatment is undermined by chronic lack of services, further compounded by limited availability of medical and diagnostic equipment.
Due to a limited availability of normal bone marrow, group I (inactive) compounds were not assayed.
In the present review we compare different materials, however, concentrating on transition metal containing compounds, as we expect that the limited availability of Rare-earth elements will hamper the industrial applicability.
Very minimal rainfall compounded with high evapotranspiration rates in this region causes limited availability of renewable water.
The limited availability of these loans could yet change.
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