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Recently however, expression of xylose transporters from C. intermedia, P. stipitis and A. thaliana was reported to improve xylose utilization in recombinant S. cerevisiae [ 9, 11, 12]; however, different experimental designs and genetic constructions in these investigations limited a functional comparison of the results.
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Network-based learning algorithms for automated function prediction (AFP) are negatively affected by the limited coverage of experimental data and limited a priori known functional annotations.
Unfortunately, the inferences that can be drawn from our results are limited by a functional annotation bias – well-studied genes are assigned many annotations while understudied genes often lack annotations.
For instance, 81% of the Swedish sample and 68% of the Norwegian sample found it problematic to assess the degree to which the reduced functional capacity limited a patient's capacity to work (p < 0.05).
Many stated it 'very problematic' to assess the degree to which the reduced functional capacity limited a patient's work capacity (47.9%) and to manage the two roles of being a physician for the patient as well as a medical expert for the SIO and other authorities (45.4%).
Excessively-high body mass limits a person's functional capacity, and compensatory maneuvers used to augment mobility by people who are overweight or obese can contribute to musculoskeletal strain.
For those species, the normalized species numbers do not converge to a limit in a functional sense, but still we can find a limit in a probabilistic sense (i.e. convergence in distribution) and their distribution.
Possibly, the 3Hz temporal limit reflects a functional adaptation of the visual system, which makes the visual system particularly insensitive to image changes that, under normal conditions, are most likely the result of eye movements.
A reliable change in scores by which at least the upper limit of a functional status is attained yields a criterion for a successful treatment [ 9].
Not surprisingly, this optimized distance (140 + 68*2 = 276 bp) is somewhat longer than the minimal space of 172 bp we identified in S. cerevisiae, which represents the lower limit of a functional promoter space.
Sickness certification involves several elements such as assessing the degree to which the reduced functional capacity limits a patient's capacity to work, to determine the optimal grade and probable duration of sick leave, and together with the patient consider advantages and disadvantages of sick leave [ 4].
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