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"I am far older than my years," Hall wrote, on the final page of his autobiography, "for I have laid aside more of the illusions and transcended more of the limitations with which I started than most".
Is public health a good that nations and global institutions can rightly seek with the same justificatory structures and limitations with which they seek national security and world peace, or is it somehow a more limited or different kind of political construct?
This is compatible with Pierret's observation that "Medicine gives the chronically ill reason to hope, even as it produces limitations with which these persons have to live by making adjustments to meet everyday requirements" [[ 12]: p.12].
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For decades, physicists at CERN and elsewhere have been trying to overcome these limitations with antihydrogen, which consists of a single positron orbiting a single antiproton.
However, there are a number of important limitations with SmoothMap, which provided motivation to develop an alternative or complimentary software framework for GI mapping analysis.
The principal limitation was limited statistical power with which to examine incidence beyond the period of first transplantation for the less common cancers.
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However, one of its major limitations is the ease with which researchers can misinterpret their results when anxious to "prove" the validity of a model or to attempt to assess causality in the relation between two or among more variables when the research design does not allow for such conclusions.
This means accepting the limitations you're working with, which is hard for any creative to do.
As with every simulation exercise, the model form, parameters and assumptions present potential limitations to the confidence with which inferences from the analysis can be made to real-life scenarios.
Thus, despite its advantages for the experimental evaluation of stress reactivity, saliva has clear limitations as a matrix with which to assess basal cortisol profiles longitudinally in natural settings.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com