Exact(1)
Although aware that the absence of sequenced mRNA sample replicates (technical or biological) implies in limitations to test differential expression based on sequence data, we presented further indications that the sequence data regarding the "gene counts" fitted very properly.
Similar(59)
The proposed algorithm is able to take into account experimental limitations due to test facilities or examinee.
To overcome these limitations and to test these ideas at the molecular level, we present here the results of receptor-focused in-silico docking of nine marketed drugs to 19 different wild-type and mutated kinases chosen from a wide range of families.
To overcome these limitations and to test the general validity of the trade-off hypothesis assumptions for a plant-virus system, we have analysed the interaction of three CMV isolates with 21 A. thaliana accessions.
To partially overcome this limitation and to test that our findings were neither biased by the size of the observation window nor the speed of stimulation, we used different playback velocities for naturalistic light intensity series (Fig. 4A).
These limitations oblige researchers to test specific and explicit hypotheses individually and independently from others.
Despite these limitations, we decided to test our hypothesis with a reasonable number of candidate TFs and by using a fast genetic approach.
With this approach, due to practical limitations, we chose to test MI in twins and with respect to factor loadings and thresholds only, similar to the metric invariance and strong factorial invariance tests respectively in the between group MI tests.
It is plausible that our failure to prove our hypotheses may have been due to test limitations typical in such high-TB burden settings.
In spite of these limitations, we were able to test the associations between metals and FT4 and FT3, which often were not measured in prior studies.
Because this was a cross-sectional study, one of its limitations was the impossibility to test the sensitivity and responsiveness of the instrument.
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