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However, paucity of available data, scarcity of compound bioavailability and metabolism information, strong heterogeneity among experimental methodologies and a number of limitations to study designs, still limit the interpretation of the results obtained through these measures.
The aim of this study was to gather information about nutraceutical values, ecogenomics data, and issues related to handling ecogenomics data and to identify limitations to study influences of climatic changes that may lead to design appropriate conservation strategies, despite existence of multiple constraints for conservation implications against climate change adaptations.
Studies were excluded if serious limitations to study quality and major uncertainty about directness existed.
There were limitations to study design and data extrapolation that should be addressed.
There are important limitations to study gene expression from in vivo oral samples, including RNA instability and amounts of sampling material, but a sequencing approach of total cDNA from an in vitro oral biofilm model has recently been performed [ 15].
For example, results from randomized controlled trials (RCTs) may be downgraded from "high" to "moderate" quality if there are methodological shortcomings such as lack of precision, the possibility of reporting bias or other limitations to study quality.
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Fowler acknowledges that there are limitations to the study.
There are a few important limitations to the study.
We acknowledge limitations to our study.
There were other limitations to this study.
There were limitations to our study.
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