Exact(3)
These include insufficient method validation, misinterpretation of raw data, lack of awareness of assay limitations, sample contamination and poor in-house assay design.
aInternal validity limitations: sample size in 5, methodological bias in 3, and multiple statistical comparisons in 1. Animals in the publications were nonrodent/nonrabbit- baboon (1), dog (3), pig (17), sheep (2); rodent/rabbit- mouse (17), rabbit (5), and rat (32).
This study has several potential limitations: sample sizes are relatively small, particularly amongst younger age-groups; data may not be directly generalizable to other regions or non-hospital communities; due to the time-course of the outbreak, sample sizes and use of chemoprophylaxis, the study was not designed to provide data on rates of progression amongst IGRA positive individuals.
Similar(57)
Due to pre‐packaged reagent limitations samples should be submitted in multiples of 16 (e.g. 16, 32, 48, etc.).
The study did have some limitations, sampling more women and city residents — 152 urban districts compared with 112 rural villages.
Only one mPrT study was not biased by co-interventions [ 71] but had other limitation (sample size and baseline imbalances).
Our study has several limitations including a limited sample size.
One limitation was the limited sample size.
So in practice there are limitations on sample size, but also on sample density and as such the method is best suited to studying moderate-to-low density samples containing heavy elements (high atomic numbers—high energy K-edges).
Due to limitations on sample, all tests could not be carried out on all volunteer samples (Table 2).
Limitations: Our sample size was modest.
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