Sentence examples for limitations of observing from inspiring English sources

Additionally, the limitations of observing large chromosomal rearrangements using only Illumina (or other short read technology), obligates the use of a combined sequencing approach for forensic investigations.

He did this by founding both the legality of this power and the wisdom of observing the limitations which hedged its proper use upon the nature of the body politic as a political society comprising both ruler and ruled — and his statement of sovereignty was the necessary, only possible, result (124 125).

However, depending on the number of analyses conducted, this adjustment, in conjunction with power limitations, may significantly reduce the likelihood of observing a true effect [ 9].

Heterogeneity in clinical features in patients with metastatic disease (Sorbye et al, 2007) may represent a major limitation for observing actual pharmacogenetic effects of functional germline polymorphisms.

The numbers of limitations observed in the domain of PF are presented in table 2. Nearly all limitations reported by our subjects were found in items 3a, b, d, f and g.

The increased rate of limitations observed possibly reflects differences in long-held, generational attitudes about end-of-life care.

Because asthma incidence was identified and projected from 14 years of observed data, a limitation is that it is possible for physician and patient behavior to have changed and for the diagnosis of asthma to have improved, meaning that the validation done previously would no longer be appropriate.

While the similarities are encouraging, the potential validity and limitations of the differences observed are discussed.

In our study we minimized this limitation by observing the digital display of the pressure-time inspiratory plateau curve thus avoiding respiratory cycles that revealed clear inspiratory efforts of the patients.

This method bypasses the limitation of twilight observing when the ecliptic is located at a low elevation (e.g. on autumn evenings).

Despite these limitations, we observed an incidence of 8% in the whole group, which is in line with an earlier report of 6% in a large international cohort study [ 16].