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Since the use of freshly excised human skin for experimental investigations meets with ethical and practical limitations, information on XME in models comes in the focus including non-human mammalian species and in vitro skin models.
Among limitations, information on MetS components was based on self-reported data from a questionnaire, which collected history of diabetes, treated hypertension, and treated hyperlipidaemia, rather than direct measurements of fasting plasma glucose, blood pressure, triglycerides and HDL cholesterol.
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The authors of the 2011 EOI analysis acknowledged that "Amongst the limitations is the limited information on how the recurrences were treated.
As a cohort study with multiple outcomes, a major limitation is the limited information on the exposure.
It should be noted here that a potential limitation is the limited information on PNC services compared to ANC services available from the DHS.
Key limitations included the very limited information on results available and the constrained feasibility of comparison with single-agency programmes.
However, our study had a number of limitations: Information was missing on smoking and BMI in a large proportion of women.
Due to data limitations, however, information on OJT is defined relatively broadly as participation in occupation-oriented courses.
This study had other minor limitations, including information on potential covariates available only from the birth certificate.
This study also had several limitations: First, information on fish consumption was based on recall, which can lead to inaccurate estimates.
It may be a limitation that information on seniority as well as musculoskeletal symptoms was based on self-reports, which may involve recall bias and differential misclassification.
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