However, we do not feel these limitations change the main conclusions of our study.
While this is not a great big deal for most people, it is good to know in case the legal limitations change.
As diluted bdHSSL was compensated for sugars and salts in order to avoid nutrient limitation, changes in μmax were assumed to be caused by the presence of the inhibitory compounds only.
By contrast, in patients with expiratory flow limitation, changes in ventilation, such as an increase in flow and/or in breathing frequency, can elevate FRC above V r.
Although the requirement for a consistent format of the SensorMedic PFT data would appear to be a limitation, changes in the format of the underlying electronic health record data requires substantial revision of many parts of the extract, transform and load process.
There is little evidence that pain and activity limitation change in concert with desirable changes to movement patterns.
Because the groups' mean scores were almost identical, we do not feel this limitation changed our results.
Non-compliers showed no difference in their: (i) baseline age, gender, episode duration, general health, depression, low back pain intensity, activity limitation, sick leave, making a LBP-related insurance claim, physically strenuous work, or job satisfaction, nor their (ii) 12 month activity limitation, change in activity limitation from baseline, or sick leave.
Latent growth curve models were used to test whether: 1) baseline physical activity was associated with baseline work limitations; 2) changes in physical activity were related to changes in work limitations; and 3) baseline physical activity predicted changes in work limitations.
For example, disease-related physical limitations predict changes in subsequent depressive symptoms over time, but depressive symptoms do not predict corresponding changes in physical limitations (15).
