Sentence examples for limitations and significant from inspiring English sources

Limitations and significant variability were identified in components of prenatal education, screening, follow-up, diagnosis, management, and program management.

Each of these approaches has serious limitations, and significant progress has only been made by combinations of more than one.

However, with regard to methodological limitations and significant heterogeneity, medical decisions should be based on both clinical findings and PCT test results.

While the evaluation of outcomes of this study in this manner may be useful, there are inherent limitations and significant disadvantages.

In table 3 the results of the multiple linear regression analyses with correction for dependence within patient clusters, gender, age, centre of treatment, duration of functional limitations, and significant prognostic variables are presented.

The results indicated that uncertainty in the characteristics of the masonry infills has the greatest impact on the response parameters corresponding to the limit states of damage limitation and significant damage, whereas the structural response at the near-collapse limit state is most sensitive to the ultimate rotation of the columns or to the cracking strength of the masonry infills.

While dialysis and transplantation provide life-saving treatments, these therapies are rife with limitations and place significant burdens on patients and healthcare systems.

The structure of these molecules features more than one fluorine atom, therefore posing limitations and posing significant challenges in regard to their radiosynthesis and the obtainable molar radioactivity.

Considering these limitations and the significant individual and societal burden of the condition, there is a critical need for development of treatment options that are effective and acceptable to this patient demographic.

The indirect nature of the comparison from the meta-analysis of arthroplasty versus internal fixation, and the small sample sizes, methodological limitations, and non-significant pooled estimates from the direct comparisons, leaves the issue very much in doubt.

Numerous problems exist for current treatment strategies for chondral and osteochondral defects including but not limited to donor site morbidity, multiple surgeries required, prolonged limitations in activity, and significant financial costs [ 7- 10].