However, the main limitation to the spatial resolution still comes from the light scattering and absorption in the tissue, like in CCD-based acquisitions, and can only be overcome with a proper inverse model for the light transport.
Lithospheric magnetic data being collected using the state-of-the-art Swarm magnetic field mission launched in November 2013 (Olsen et al. 2013) will still have limitations related to spatial wavelengths, i.e., shorter wavelength components can only be revealed by near-surface surveys.
This asymmetry in old/new recognition performance is easily explained by the well-known limitations of the human visual system, including its increasingly poor processing of higher spatial frequencies due to the acuity limitations related to spatial density and distribution of rods and cones on human retina [35] [37].
In addition to this, the relatively large PH size (~3 µm) does not pose any limitations to achievable spatial resolution (unlike the reflection mode discussed earlier) since there is a large demagnification factor of > 25 fold in this hologram recording geometry (i.e., zPS > 25 zSS).
Conventional radionuclide perfusion scintigraphy has been used to assess these abnormalities, but it has substantial limitations with respect to spatial and temporal resolution.
For the diagnosis of small (<1 cm) lesions, fat suppressed MRI techniques (like CT) may also fail to detect gross fat; with limitations related primarily to spatial mis-registration from varying breath-holds between pulse sequences.
However, it should be pointed out that μPET imaging in mice still has major limitations with regards to spatial resolution of currently available μPET scanners, attenuation correction and correct quantification, as well as anesthesia-induced changes of radiotracer uptake.
The increase in H2O2 production and decrease in the charge transfer number is ascribed to spatial limitations arising from the adsorption of the contaminants because the rupture of the O-O bond requires two adjacent Pt active sites.
This topology is especially attractive for large complexes: due to spatial limitations, it is unlikely that all proteins in a large complex can interact with all others.
Twelve clusters covering auditory cortex also appeared to include the insula (all of which were gamma-range clusters, i.e. >30 Hz), although due to spatial limitations, we cannot be confident whether this represents true insula activity or spillover from auditory cortex.
