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An obvious limitation to implementation of the multivariate models presented in this paper is the limited availability of data including i) the problem of missing within-study correlations and ii) the requirement for a relatively large number of studies to estimate all model parameters.
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In this article, the authors have evaluated the development, challenges, and limitations to implementation of REACH in the occupational setting in order to examine to what extent the REACH 'ideals' can be achieved.
The constraints generated by their complexity and the costly access to useful energy planning tools is a limitation to their implementation.
Spoilage of vaccines due to flaws in the cold chain is widely considered to be a major problem, and a key limitation to full implementation of the Global Immunization Vision and Strategy (GIVS) [ 27].
The main limitation to the implementation of an online logbook is the compliance of users and supervisors to exploit the potential for quality improvement this tool can offer: motivation is key to support and improve accuracy and completeness of the data entered.
The vast majority of respondents welcomed the promotion of EBM in family practice; however, participants also enumerated a significant list of barriers and limitations pertaining to implementation (Table 2).
The aperture problem also constitutes a limitation to their straightforward implementation.
This is an important finding, and has been perceived as the key limitation to the successful implementation of patient-centred care [ 7, 15, 16, 33].
There are certain limitations to the implementation of such hierarchical scheme.
One of the major limitations to the implementation of amine based post-combustion CO2 capture (PCC) technology is the high efficiency loss induced by the process.
Tumor growth inhibition via anti-angiogenic therapy has certain practical limitations to its implementation [12].
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