This limitation may help to explain the low concordance for some of the medical conditions analyzed in this study.
This limitation might contribute to explain help-seeking for mental health problems in individuals without current symptoms.
Two main proximate limiting factors, pollen limitation and resource limitation, have been proposed to explain these common phenomena (Haig and Westoby 1988).
Third, these two processes – the habitat niche and dispersal-limitation – are used to explain stand-scale diversity, in addition to the role of neutral effects (habitat area).
5 These authors highlight the pitfalls of making this assignment retrospectively after clinical assessment, suggesting that basing judgement of appropriateness on information available after the contact (ie, a firm diagnosis) has many limitations in seeking to explain variation by clinical symptoms.
Dispersal limitation has been invoked to explain the clumped distribution of adults and limited recruitment of seedlings in both A. erinacea in Ecuador and A. minima in Puerto Rico.
The h-I estimates had limitations and we cannot rule out that these limitations might be able to explain the absence of clear and independent prognostic values [7] [10], [16] [17], [ 25].
The secondary use of existing data is not necessarily less credible, but a statement might help to explain limitations in the study, including, but not limited to, relevant data not being assessed or the presence of peculiar population characteristics.
However the limitations in our ability to explain the heterogeneity do not invalidate the result that, in general, TT individuals have a higher ischaemic heart disease risk than CC individuals.
Given these limitations, if we have to explain reduced mean diffusivity in white matter based on our histopathological results, it would seem most likely due to astrogliosis and microgliomatosis.
