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Another limitation of localization microscopy is the lack of three-dimensional (3D) information.
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The limitation and localization of the inter-MS channels contrast with the typical assumption of unlimited and global connectivity among the BSs via the high-capacity backbone [3, 6, 7], which is reasonable due to topological and infrastructure constraints.
An inherent limitation of metabolic network-based localization prediction is that it is strictly limited to metabolic enzymes.
To overcome this limitation, spectral precision distance microscopy, a method of localization microscopy at the nanometer scale, was used to measure 3D distances between differentially labeled probes located both within the PWS region and in its neighborhood.
Localization and limitation of connectivity in the network are intended to mimic cortical connectivity, partially because of the clear retention of retinal topology through regions of visual cortex.
The labelled IL-2 derivatives showed good results in terms of localization of the inflammation within the limitations of gamma camera imaging.
The inherent limitations of DOA-based localization method specifically for indoor environment and under low sampling rate are initially discussed.
Thus, it is important to understand the capabilities and limitations of existing position localization technologies and their role in enabling and constraining application development and deployment.
This avoids making the inaccurate assumption that specific sensors correspond across individuals despite different head shapes and orientations, although results must be interpreted within the limitations of MEG source localization accuracy.
So the inability to directly examine HP1E chromatin localization is an acceptable limitation of the system.
"For listeners, it leads to a lack of localization".
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