We appreciate the limitations of exploring small numbers using logistic regression, and we do not believe that our failure to identify statistically significant risk factors implies lack of effect.
Available ASE analysis tools [ 4, 5, 13- 15] either require trios, i.e. genomic information from individual's parents, or solely rely on RNA-seq data with limitations in terms of exploring large datasets or in potential high false positive rates, respectively.
We recognize the limitation of not exploring the experiences of service providers and service users.
The limited detection options available impose practical limitations to exploring all the possibilities of the method because in principle, every kind of sample consisting of a solvent and a dissolved or dispersed phase can be investigated in an AUC.
Content analysis was chosen because it is an inductive process, involving openness to whatever the participants said, though within the limitations of the study's purpose of exploring management strategies.
There are other limitations, principally arising from the methodology of exploring HRQL, previously un-researched in this sample in which HRQL had not been assessed using existing dementia-specific measures.
First, because nothing sets you (or at least me) free creatively like having a set of limitations to explore.
A major limitation of existing studies exploring the relationship between suicidal behaviour and geographical location is that they conceptualise location as a dichotomous construct, exploring 'urban' versus 'rural' areas, and frequently under-represent remote and very remote residents [ 16].
These approaches have produced significant insight into the metatranscriptome of different communities but have limitations when exploring the diversity of natural communities.
You are forced to meet new people you know nothing about, push yourself out of limitations and explore areas out of your own comfort zone.
