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A fourth category of abnormal gas exchange involves limitation of diffusion of gases across the thin membrane separating the alveoli from the pulmonary capillaries.
Due to limitation of diffusion equation and its approximated nature, we want to explore the accuracy and precision of this method.
Hypoxaemia in critical illness may be caused by hypo-ventilation, ventilation/perfusion mismatch, right-to-left shunting or limitation of diffusion across the alveolar capillary membrane.
Bacteria in deep layers of the biofilm are more resistant due to the limitation of diffusion (photosensitizer, oxygen or light or the irrigating agent) through the organic structure [ 29].
A major limitation of diffusion sensitized SS-EPI imaging is magnetic susceptibility artifacts, at different tissue interfaces common in musculoskeletal imaging, such as bone and soft tissue, which can lead to severe geometric image distortion, relatively low spatial resolution due to rapid T2* decay of signal, and in general low image quality.
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Mechanisms of abnormal gas exchange are grouped into four categories—hypoventilation, shunting, ventilation blood flow imbalance, and limitations of diffusion.
High-definition fiber tractography (HDFT) is an optimized diffusion MRI technique that overcomes many of the limitations of diffusion tensor imaging (DTI).
We also acknowledge the limitations of diffusion tractography.
Potential limitations of diffusion imaging such as complex crossing fibre microstructure, reliability and reproducibility, are being addressed through novel diffusion MRI acquisition and analysis techniques [ 29].
Drug injected into the cerebrospinal fluid rapidly moves into the blood via bulk flow, but penetrates into brain tissue poorly owing to the limitations of diffusion.
This study suffered from the general limitations of diffusion tensor modelling and tractography approaches (for a recent review with specific reference to the domain of language see Campbell & Pike, 2013).
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