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Correspondingly, there are many plausible variations within the RBC limitation framework.
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Due to limitation of the framework, the proposed model did not separate the aforementioned cell types into different topological compartments.
In this framework, limitation of individual freedom and autonomy for the sake of the common good is an act of self-governance; such self-imposed or consensual paternalism poses no moral dilemma.
A limitation of the framework was that it does not include any hypothesis on power relationships among the team members.
One limitation of our framework is that is has yet to be vetted by these important stakeholders.
However, a major limitation in this framework is their unknown mode of action, and the lack of a specific biological target.
These observations suggest that by carefully identifying key decomposable structures within the desired response, it is possible to overcome this important limitation of the framework.
Weakness of data from developing countries is a limitation of this framework which draws on existing datasets, which we addressed by drawing on the knowledge of key informants experienced in the country health research systems to interpret the data.
While the static composition of the biomass as a component of a metabolic model is known to influence the results of FBA predictions, little had been proposed to date in order to overcome this limitation of the framework.
Finally, we discuss the strengths and limitations of this framework.
The limitations of our framework are also discussed.
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