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However, for QSARs to be accepted by the regulatory communities, their limitation for use needs to be identified.
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Our results showed that binding coefficient (KDOC) for phenanthrene is neither independent of free solute concentration, nor DOM concentration, which is a critical limitation for using FSQM in a form of Stern Volmer equation to examine HOC DOM interactions.
This means that currently the main limitation for using Velvet on larger genomes are engineering (rather than algorithmic) issues.
Ascertainment bias of the SNPs present in this dataset is a known limitation for using the data for population genetic studies[16], however we aim to compare two subsets of SNPs based on a property (NSCS vs. NS) not primarily involved in the SNP discovery process.
This is an important limitation for using the risk factor of prior antibiotic exposure in daily patient management decision making.
Another limitation for using s-Cath is the presence of sticky airways secretions, typically found in primary ALI/ARDS following bilateral pneumonia, making it impossible to obtain free-flowing oedema fluid.
However, chitosan has certain limitations for use in controlled drug delivery and tissue engineering.
However, existing computer models are still rudimentary with many limitations for use in early design stages of any architectural project.
The current vaccine, an inactivated whole virus preparation, has a number of limitations for use in outbreaks in disease-free countries.
Rationalising these biochemical features in relation to the chemically and physically harsh environments inhabited by these organisms and evaluating their potential (and limitations) for use in industrial biotechnology can form the basis of a range of profitable student study topics.
The traditional tanks employed in natural gas storage by adsorption reveal serious limitations for use in fast charge systems because of their inefficiency in the dissipation of adsorption heat.
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