Sentence examples for limitation for developing from inspiring English sources

hAMSCs are known to have decreased proliferative capacity in current normoxic cell culture conditions, which will be a limitation for developing cellular therapies.

However, as indicated, one major limitation for developing imino sugar antivirals has been the lack of potency and/or poor pharmacokinetic properties, which lead to difficulty in maintaining therapeutic drug concentrations in vivo.

This is an usual observation in pine and other highly polymorphic species, and a common limitation for developing traditional genotyping methods, such as SNP chips (Eckert et al. 2009; Grattapaglia et al. 2011).

The inability of conventional methods to identify these disorders earlier and better than clinicians, and the recent failure of promising therapeutic compounds, highlight the fact that the lack of biomarkers is probably the greatest limitation for developing treatments for these disorders.

The inability of conventional methods such as MRI to identify these disorders earlier and better than clinicians, and the recent failure of promising therapeutic compounds based on rational therapeutic hypotheses [ 36] highlight the fact that the lack of biomarkers is probably the greatest limitation for developing treatments for these disorders.

This limitation is the motivation for developing techniques that still utilize the full dimensionality of the data without exhaustively searching all possible combinations of variables with the goal of discovering a well-fitting model that explains variance in an outcome of interest.

This renders ARMS-DCA – despite its limitations – a good choice for developing assays facilitating e.g. the pre-screening of large population samples in order to identify the relevant DNA extracts or the fast and cost-efficient mtDNA based exclusion of innocent individuals in DNA dragnets.

Within the "make-or-buy" context, it was determined that there are significant limitations in domestic manufacturing for developing countries.

Merits and limitations of using the CEFR for developing the speaking assessment (i.e., applicability of the CEFR for TOPE) were discussed.

The capabilities and limitations of the Java platform for developing and supporting such Internet based distributed engineering software tools are discussed herein.

The presence of terrain- or distance-related barriers assessed with the same scale doubled the risk for developing outdoor mobility limitation over a 3.5-year period in a previous study [ 7].