Exact(1)
The lack of measurement of C-peptide levels during clamps is another potential limitation; endogenous insulin contributions to PK/PD parameters cannot be directly assessed.
Similar(59)
Immature detection and appraisal of rewards coupled with limitations in endogenous impulse control could result in poor decision making that may then set the stage for engaging in risk taking.
Exo, exogenous; Endo, endogenous.
My hypothesis is that one of the endogenous limitations of these tendencies is the fragmentation and specialisation of problems.
This article reviews the biology of these systems, their application in drug delivery, and the promises and limitations of these endogenous systems for drug delivery.
We have identified significant limitations to the endogenous regenerative response of the SEZ at post-acute time-points post-injury; dependency on direct involvement in the lesion and a loss of NSC activation at later time-points.
While the TBARS assay is relatively insensitive and has a significant number of limitations for assessing endogenous oxidative stress, it was appropriate to assess the effect of MitoC on preventing lipid peroxidation in vitro induced by exogenous oxidants.
Unfortunately, available reporter proteins have numerous limitations including their endogenous expression in diverse cells and tissues, lack of convenient cloning sites and potential interactions with intra- or extracellular proteins that may affect their subcellular distributions [ 12].
However, we have encountered technical limitations in detecting the endogenous Fbw7 protein in our tumor lysates.
Content and activity of low-molecular antioxidants and antioxidant enzymes activators may play the crucial role in creating the prohealth properties of plant-derived food; however, equally important is limitation of ROS generation by endogenous factors.
Owing to technical limitations, the co-localization of endogenous ULK3 and IST1 cannot be determined because both antibodies were raised in rabbits.
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