However streamlining is applied after antimicrobial therapies have been initiated, allowing some degree of inappropriate exposure in addition to the potential limitation of effectiveness derived from the voluntary nature of its compliance [ 3, 22].
In any case, it is recognised that mosquito repellents have limitations of effectiveness so that users may suffer occasional bites.
Physicians seldom attempted to explain to patients the limitations of effectiveness or to encourage them to stop taking the eye drops.
Issues such as the wider cultural context, inequality, transportation system limitations, cost effectiveness, health system strengthening and sustainability all need to be considered and integrated [ 23, 43].
Non-specific chronic low back pain (NSCLBP) has become a significant problem due to high healthcare utilization, rising costs of care and perceived limitations of effectiveness of many current treatments.
The economic evaluation will examine differences between participants in the Rehabilitation and Advice groups in terms of costs incurred and changes in perceived activity limitation (cost-effectiveness analysis) or utility gained (cost-utility analysis).
Targeting this age group has an important potential impact given the current limitations in effectiveness of adult interventions [ 12], the wide coverage of maternal and infant programs and the lower cost of using existing resources.
In ecoregion cluster 3, tick populations suffer drastic limitations in effectiveness because of low and inadequate rainfall [ 46], and this high selection pressure on tick populations might be adverse for pathogen transmission and selection.
This study provides data to support, within limitations, the effectiveness and safety of clinical practice of OMT in Australia, and pragmatic trials of osteopathic practice should be undertaken to provide stronger evidence for osteopathic practice as a complex intervention to inform other health care practitioners and patients on the scope of osteopathy, its effectiveness and safety.
Finally, it became apparent during the interviews that an important limitation on the effectiveness of the CAB – insofar as its effectiveness is linked to the involvement of the wider community – was the fact that few CAB members discussed their CAB membership or role with more than a very small subset of community members.
